Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
China’s investment in Europe and the US has reached record highs, despite the slowdown in the country’s domestic economy.
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
The stomach-churning finding is not the first to be exposed in the area. Police in Guangxi, along China's border with Vietnam, have stepped up anti-smuggling operations over the last year and have raided seven illegal food processors.
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
节目30 相声，郭德纲 于谦
This story pulls directly from the real Bling Ring gang , whose burglaries racked up $3 million over the span of ten months in 2008. All of the celebrities listed in the movie were real victims of this group, who claim to have been motivated by the "cultural obsession" surrounding celebrities' personal lives. Whatever their motives, the Bling Ring is a good reminder to take a step back from the media every once in a while.
'The pizza is extremely rich - if you're in the mood for a lavish meal, this is the pizza for you,' he said.
Trends and targets in antiviral phototherapy
The demagogue’s campaign leads naturally to despotism — the tyranny of the majority that is a mask on the tyranny of one.
Much of the decline in Chinese imports stems from lower commodity prices, which in turn are a result of falling overall demand from China, long the world’s biggest consumer of materials such as iron ore, coal and copper.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
It was not an auspicious start to the new year for bitcoin investors.
Novel biosensing methodologies for ultrasensitive detection of viruses
An early iteration of Summly, called Trimit, was featured in Apple's app store in July 2011 on a list of new and noteworthy offerings. There it was noticed by the influential Silicon Valley blog TechCrunch and quickly came to the attention of an investment group led by Li Ka-shing. When D'Aloisio was approached over email by Li's people at Horizons Ventures, he was only 15-and so far mostly managed to conceal that fact. He'd never met with anyone in the tech world face to face, and the information he'd listed when he registered Trimit spoke only vaguely of a London technology company. It failed to mention that the company's management and technology teams-in fact, its entire workforce-consisted of a single kid in a suburban bedroom who wasn't yet old enough to drive.
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
ACE2 as a potential therapeutic target for pandemic COVID-19
Coca-Cola (KO, Fortune 500) Chief Executive Muhtar Kent thinks as both a first-generation American as well as a business leader that immigration reform is good for business. Kent outlined in a February USA Today op-ed how "lucky" he felt to be able to make his life in the U.S. and his belief that foreign entrepreneurs should have the same opportunity. The CEO wrote that he supports immigration reform because immigration is "an essential part of the growth calculus for this great country."
Diagnostic technologies for COVID-19: a review
Harvard Business School, London Business School (LBS) and MIT Sloan School of Management, three of the MBA ranking’s longstanding heavyweights, all lost ground to their competitors. Harvard drops two places to fourth, the first time in nine years that the Boston school has been outside the top three. London Business School falls three places to sixth, its lowest position in 14 years. MIT Sloan School of Management falls to 13th place, the first time in 10 years that it has been outside the top 10.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
"This is something we believe is really important for the future of our country,"Facebook (FB, Fortune 500) CEO Mark Zuckerberg said in August.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
The world got by in 2013 with fewer confidence-shaking moments than in prior years. But the vulnerabilities haven't disappeared. 'It's not a great story anywhere, though it's more hopeful than it has been,' said Jerry Webman, chief economist at OppenheimerFunds.
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Leatrice Eiseman, the executive director of the Pantone Color Institute, said the joining of the two colors reflected “a soothing sense of order and peace” — presumably an attractive thing to incorporate into a product at a time of insecurity and global turbulence. It also implies that there is no line between “us” and “them.”
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
Dealers: Car dealers work toward reducing the paperwork involved in buying a car and the hours it takes to fill it out. That will give them more time to devote to upselling add-ons such as extended warranties, paint and fabric protection, and rust-proofing.
Influenza neuraminidase: A druggable target for natural products
Those concerns are casting a heavy shadow over a two-day meeting of G20 central bank governors and finance ministers due to start tomorrow. The International Monetary Fund this week already warned that it was poised to downgrade its forecast for global growth this year, saying the leading economies needed to do more to boost growth.
President Donald Trump is the nation's first billionaire president -- but he's not as rich as he used to be, according to the Forbes 2017 Billionaires List published last Monday.
The China International Robot Industry Summit, held on Tuesday in Shanghai, said the sales and growth rate of industrial robots hit records in 2017. Among industrial robots, 37,825 were domestically manufactured, up 29.8% year-on-year.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Two United States cities have seen significant increases in costs, with Los Angeles rising 19 places to enter the top 10.
The role of biosensors in the detection of emerging infectious diseases
If managers suspect you're looking elsewhere, your LinkedIn profile is often the first place they'll snoop, says Jenny Foss, founder of the career blog JobJenny.com and author of "Ridiculously Awesome Job Search Kit." "It's where a lot of people tend to get busted," she adds。
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
British schools outperform the French on both new criteria. Warwick Business School, the top UK school for career progress, is second overall for the criterion, 30 places above the first French school, HEC Paris. Alumni from UK schools also see a higher increase between their first salary after graduation and now, at 62 per cent versus 45 per cent. However, UK school alumni still have a lower salary on average than their counterparts who studied in France, at $55,000 versus $64,000.
After her legal travails , anything Kesha released would have a veneer of triumph. But this comeback set was an artistic warrior cry more potent than any might've expected.
“Yao represents the new wave of wealth creation by financial investments in China,” said Rupert Hoogewerf, who compiles the annual list.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
11. Am I dwelling on the past? It is very tempting and almost involuntary to look back on the past and obsess over something we regret or something we miss. Learn to let go and only focus on what’s happening right now, and on the choices you will make today.
Inhibition of SARS coronavirus helicase by bismuth complexes
Whatever one's view, two further points for and against Russia's global standing are undeniable:
Frances McDormand giving an outstanding central performance as a grieving mother in this darkly comic story.
Now the burden is on Noel to prove that he's capable of being more than the shell of a player he often looked like amidst the Sixers' disarray.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
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A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Iron ore imports fell 12.3 per cent by volume in October from the previous month and 4.9 per cent from the same month a year earlier while coal imports were down 21.4 per cent from September and 30.7 per cent from a year earlier, according to Chinese customs data.
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Will China’s reported gross domestic product growth surpass 6.5 per cent
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Mr. Lyons took a casting of Ms. Swinton’s mouth and designed teeth to fit. Those were clipped on over Ms. Swinton’s real teeth. For Minister Mason, he came up with a quirky look but didn’t quite want it to be comical. He was, however, interested in adding a little bling. “There’s a little bit of gold on the left-hand side,” he said. “We used real gold to make the filling of one tooth. We did it to put more character into the character.”
9. Occupational therapist
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
除了P2P贷款领域发展迅速以外，今年还涌现出一些网络银行和贷款机构——比如腾讯(Tencent)的微众银行(WeBank)、阿里巴巴(Alibaba)的网商银行(Mybank)，以及蚂蚁金融(Ant Financial)的芝麻贷(Sesame Credit)。
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
As computer programming is being hailed as the untapped opportunity in the American economy, New York Code and Design Academy is making it easier to speak code. By 2020 there will be 1.5 million computer science jobs with only 400, 000 computer science graduates. Moreover, computer science jobs are growing at twice the national average as other positions. But what if you didn’t graduate with a computer science degree, and have no plans to go back to college? New York Code and Design Academy is making it easier to learn web design and development by offering both night programs and intensive workshops — where it’s not uncommon for someone to walk out of the program having built a new website or setting sights on a new tech-based position at work. From where Founder Jeremy Snepar sits, you can’t afford to not know how to code in today’s digital economy. He sees coding as a technical skill that can and should be easier to learn, and New York Code and Design Academy is filling an important gap for anyone who’s ever said “if only I knew how to code.”
Import growth lifted year-on-year to a pace of 17.7 per cent for the period, up from 17.2 per cent a month earlier and beating an expected rate of 11.3 per cent.
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
German Three:Mercedes-Benz begins to sag as new lower-priced Benz’s inevitably erode its once invincible “the best or nothing” status. At BMW, imminent arrival of a new 7-series cements its status as the preferred brand of Scarsdale, Shaker Heights, and Santa Monica. A new A3, starting at $30, 795, should nicely lift Audi’s sales beyond 2014’s 15% climb, and a new Q7 SUV should nicely lift profits.
NeXT 电脑公司总裁兼CEO史蒂夫乔布斯在向公众展示他的新一代NeXT 工作站（此时乔布斯已经离开苹果创办了皮克斯动画和NeXT 电脑公司），1990年9月18日，旧金山
回购股票会帮助推高股价，很多分析师将标准普尔500（Standard & Poor's 500 index）创下多次历史新高归功于股票回购的盛行。
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
"How to tie a tie" was the No. 1 question in 2010, followed by "how to lose weight", "how to kiss" and "how to write a resume."
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
据纽约Selby Jennings的金融服务业猎头奥利弗库克(Oliver Cooke)介绍，各银行如今注重它们所称的“内部流动”，即跨部门调职。例如，如果一家银行面临债券交易低迷的情况，它可以让交易员转岗成为风险分析师或合规官，此举可以保持员工的兴趣——同时节省一大笔遣散费。
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
*剧情类最佳客串男演员：汉克?阿兹利亚(Hank Azaria)，《清道夫》(Ray Donovan)
After Zhou contaminated the water, one of Zhou's classmates surnamed Tang noticed that the water coming out of the dispenser was milky and had a pungent scent.
Helu came in fourth in Forbes' 2016 list of 1,810 billionaires, behind Gates, Zara's Amancio Ortega and business mogul Warren Buffett, respectively.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
“If we can identify someone who buys in both places, there is huge value there. You know who they are, what they bought, what they spent,” Harper added. “You can give them a more personalized experience.”
Experts waited until dark had fallen before detonating demolition charges which brought down 150000 square metres of concrete glass and steel in 10 seconds.
Three Billboards Outside Ebbing, Missouri
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
A lighthearted rom-com starring Adam Sandler and Drew Barrymore is the last thing you'd expect to mirror real life, but this comedy was in fact partially based on a true story. Sandler plays a veterinarian who falls in love with Barrymore, an amnesiac whose memory resets at the beginning of each day. He learns that Barrymore has replayed the same day over and over again since a car crash left her with a traumatic brain injury. Upset by the lie she has been living, Sandler's character makes a series of videos that explain her accident and her life for her to watch each morning.
An international medical journal's retraction of 107 research papers from China, many of them by clinical doctors, has reignited concerns over academic credibility in the country.
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
When asked if the central bank would do more, Dario Perkins, chief European economist at Lombard Street Research, said: “I don’t think so, unless something goes wrong in the wider global economy.”
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Stand: Facebook CEO Mark Zuckerberg took a stand for immigration reform
A modular microarray imaging system for highly specific COVID-19 antibody testing
1.Photography: 22.3 percent increase
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
She emotes with some of Pink's husky attitude and some of Sia's theatrical so-over-it-ness, but she's a warmer singer than either, whether shrugging off a lover on the self-explanatory "IDGAF" or matching Miguel's intensity on the steamy "Lost in Your Light."
So, what does that mean for oil prices in 2015? It is anybody’s guess, but here are the top five variables that will determine the trajectory of oil prices over the next 12 months, in no particular order.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
The captain must steer the ship. If leadership doesn’t know where a project or company is headed, how can the company know? This isn’t just about steps or deliverables, either, but a clear vision of the department or company’s future that he or she can communicate to the employees。
China's economy grew last month, according to a closely-monitored PMI series - which indicated growth for the first time in four months.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
6. China will also soonmake further announcements regarding affordable housing and more accessiblehealthcare. The country still needs 75 million more $75,000 housing unitsand it will begin breaking ground on them, in earnest, in 2014. Theseinvestments, particularly in health care, will effectively become self-funded,allowing average Chinese consumers to consider saving less, and spending more. It will drive longevity and years of productive employment.
A research team at the University of Chicago has solved this problem, producing hands that send electric signals to the brain. They've begun with monkeys as test subjects, studying the animals to see how their brains respond to touch. When outfitted with prosthetic hands that stimulate their brains that way, the monkeys respond just as though they physically touch objects themselves.
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
China’s tourism administration issued a notice on Friday confirming reports that Chinese travellers had been denied entry to South Korea’s Jeju island in recent months for holding incomplete travel documentation. It reminded citizens to “select travel destinations with caution”.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
It predicts index funds, or those that track commodities indices, to be back in the agricultural market in the second half of 2017, as they look for a hedge against inflation.
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
有趣的是，“真诚的问候”(unfeigned regards)又重回我们的视野——人们现在可以在印度服务中心的邮件上见到这一18世纪末的流行语。而更胜一筹的是这个签名，一个周五我收到了一则消息，末尾处写到：“周末好”(weekend well)。我差点将最佳名词使动用法奖也颁给它，不料最后一刻却杀出一匹黑马，一位顾问无意中说了句：“我们能把那件事冷毛巾一下吗？”(Can we cold towel that?)
The survey of 11,500 workers by Chinese employment agency Zhaopin found that 50.9 per cent did not get an annual bonus at the end of 2016. Another 9.6 per cent were told their bonus had been delayed until after the new year holiday.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Like air, blue skies treat everyone equally.
At tech start-up conferences, such as Slush in Helsinki in December, everyone was talking about experiences. The coming year is likely to see a wider adoption of virtual reality, which places the user in a digitally enhanced environment, and augmented reality, which overlays digital information on to the real world, creating new digital businesses.
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Anti-HIV drug repurposing against SARS-CoV-2
Length-scale dependence of protein hydration-shell density
Collins grew up in rural, apartheid-era South Africa in the 1970s. Her childhood inspired her to focus on empowering women living below the poverty line through grassroots efforts. The Wonderbag, which was inspired by watching her grandmother cook with cushions, uses heat retention technology to cook food for 8-12 hours without the need for additional fuel. Collins witnessed the benefits African women received from using Wonderbags, reducing the amount of time they spent collecting firewood. For every bag sold, another is donated to a household in Africa, and in the past four years, the Wonderbags have found themselves in 600,000 African homes. Collins has launched the Wonderbag in the U.S. on Amazon, and hopes to sell the products via other retailers by 2014.
3. Grow your hair slightly longish, if it isn't naturally wavy (poor you), wear curlers to bed every night.
*Awards presented during the Creative Arts Emmy ceremony Sept. 10-11.
Beck “Say Goodbye” (Capitol)
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Though its campuses often steal the benefits spotlight -- with their outdoor sports facilities, free food and more -- there's a more morbid perk that should certainly be noted. If a U.S. Googler passes away while working for the tech giant, the employee's spouse or domestic partner receives 50% of the deceased's salary, no matter how long or short his tenure, every year for the next decade.
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
More provinces are falling in situations where the pension fund cannot cover the expenditures. As one of six provinces with the problem last year, Heilongjiang's enterprises pension can only pay up to one month.
Whole Foods CEO John Mackey
About this collection
With an 8.5-percent increase in profits, industrial enterprises reversed the previous year's negative growth of 2.3 percent.
With best wishes for a happy New Year!